About PHENPRES 1ML/10MG Injection
PHENPRES 1ML/10MG INJECTION - Phenylephrine Hydrochloride Injection I.P.
Brand: PHENPRES Injection
Content: Phenylephrine Hydrochloride I.P. 10 mg / 1 ml
Company / Manufacturer: Neon Laboratories Ltd
Pack: 1 ml Ampoule
Category: Anti-hypotensive Agent / Alpha-1 Adrenergic Receptor AgonistProduct Description
PHENPRES 1ml/10mg Injection contains Phenylephrine Hydrochloride, a synthetic sympathomimetic agent formulated for parenteral use. It is primarily used in operating rooms, emergency departments, and intensive care units to manage acute, clinically important low blood pressure (hypotension) resulting from vasodilation during spinal or general anesthesia. This sterile injectable medication functions effectively as a potent vasoconstrictor to restore circulatory equilibrium during surgical procedures or post-traumatic recovery phases.Key Uses
- Rapid treatment of clinically significant hypotension induced by spinal or general anesthesia during surgical operations
- Management of acute hypotensive states and circulatory shock conditions
- Prevention of blood pressure drops in pediatric and adult patients undergoing medical interventions
How It Works
Phenylephrine is a powerful, selective alpha-1 adrenergic receptor agonist. It acts directly on the alpha receptors situated within the smooth muscles of systemic blood vessels. By triggering these specific biological targets, it induces localized constriction and narrowing of the arterioles. This vasoconstriction cycle systematically elevates systemic vascular resistance, causing a rapid and controlled rise in systemic blood pressure accompanied by a minor, compensatory reduction in heart rate.Directions for Use
- Must be diluted prior to administration as an intravenous bolus or continuous intravenous infusion
- Can be administered via intravenous, intramuscular, or subcutaneous injection based on clinical urgency
- Visually inspect the sterile fluid inside the glass ampoule for structural sediment or discoloration before drawing
- Must be prepared and administered exclusively by an anesthesiologist, nurse, or registered healthcare practitioner
Key Features
- Rapid therapeutic onset providing blood pressure support within minutes of venous entry
- Minimal direct central nervous system stimulation or cardiac beta-receptor interaction compared to adrenaline
- Convenient single-use 1 ml glass ampoule designed to facilitate sterile emergency deployment
- Produced in compliance with national pharmaceutical monographs under precise standards by Neon Laboratories Ltd
Possible Side Effects
- Transient headache, nervousness, restlessness, or mild tremors
- Nausea, vomiting, stomach upset, or localized sweating
- Difficulty or delay in passing urine
Important Safety Notes
- Storage Temperature: Store below 25C in a cool, dry space. Protect from direct light exposure and do not freeze.
- Monitor the active infusion site carefully; localized drug extravasation can induce severe skin tissue damage or necrosis